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Piper Clarke Oct 20, 2019 10:28:59 PM 2 min read

New Scientific Journal by Dr. Sebastian Torres, MD

Patient Satisfaction and Experience with the Use of a New Stabilized Hyaluronic Acid Dermal Filler (Intraline, Canada Inc., Kelowna BC, Canada): 10 Month Follow Up


Background: The most common request among facial rejuvenation procedures is the augmentation of the nasolabial fold.

Objective: To evaluate the safety, efficacy and patient satisfaction with the use of a new cross-linked hyaluronic acid (HA) based dermal filler (Intraline 2, Canada Inc., Kelowna BC, Canada) in reducing medium to deep nasolabial folds.

Materials and Methods: This was a single center, blind evaluator, 300-day study in which 70 patients with moderate to deep, nasolabial folds were treated at their baseline visit with up to three 1mL syringes of HA. The physician and evaluator assessed patients 7 days after treatment and then every month after the initial treatment for 10 months (300-days). Moreover, patient satisfaction was measured at 1, 3, 6 and 10m through a self-evaluation questionnaire.

Results: Subjects experienced statistically significant improvement in nasolabial folds and maintained those results for more than 240 days. In proximity of the end of the observational period (300 days) the studied area revealed minor re-absorption of the product being at all times better than baseline. Patient satisfaction scores were rather excellent or very good for all the length of the study

Conclusion: Injectable HA new cross-linked based dermal Filler (Intraline 2, Canada Inc., Kelowna BC, Canada) was efficacious in reducing medium to deep nasolabial folds, resulting in satisfactory corrections up to 300 days and excellent patient compliance and satisfaction rate.

To read full the full journal article, go here.

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